Posters & Presentations
A list of the published posters and presentations that our grants have facilitated.
ADI-PEG20 restores immunity in the tumour microenvironment and eradicates GBM tumors in mice when combined with radiation
Jake Symington1,2, Richard Perryman1, Sophie Morse1, Deborah Healey3, Chad C. Quarles3, Kevin O’Neill1, Elizabeth Want2,4, Nelofer Syed1,2.
1John Fulcher Molecular Neuro-Oncology Laboratory, Department of Brain Sciences, Imperial College, London, UK; 2Cancer Research UK Convergence Science Centre, Imperial College, London, UK; 3Division of Neuroimaging Research, Barrow Neurological Institute, Phoenix, Arizona, USA; 4Section of Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, London
Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for GBM
Richard Perryman, Alexander Renziehausen, Hamidreza Shaye, Androniki D. Kostagianni , Antonis D. Tsiailanis, Tom Thorne, Maria V. Chatziathanasiadou, Gregory B. Sivolapenko , Mohamed Ahmed El Mubarak, Gye Won Han, Barbara Zarzycka , Vsevolod Katritch , Guillaume Lebon , Cristiana Lo Nigro, Laura Lattanzio , Sophie Morse, James Choi, Kevin O’Neill, Zoe Kanaki , Apostolos Klinakis , Tim Crook, Vadim Cherezov , Andreas G. Tzakos, Nelofer Syed
Imperial College, London
Mitochondrial and Gene Expression Changes in Brain Tumor Cells Grown in β-Hydroxybutyrate
Ahmad Kareem Almekkawi1, Rachelle Sheets1, Brianna A. Werner1,2, Richard A. Perryman3, Indrapal N. Singh1,2, Mohammad A. Karim1,2, Richard E. Frye4, Nelofer Syed3, Adrienne C. Scheck1,2
1 Department of Child Health, The University of Arizona College of Medicine – Phoenix, Phoenix, AZ, USA; 2 Barrow Neurological Institute at Phoenix Children’s Hospital, Phoenix, AZ, USA; 3 John Fulcher Molecular Neuro-Oncology Laboratory, Imperial College, London, UK; 4 Rossignol Medical Center, Phoenix, AZ, USA
MULTISPECTRAL ANALYSIS FOR INTRA-OPERATIVE CHARACTERIZATION OF BRAIN TUMOURS, MARGINS OF RESECTION, AND ELOQUENT AREAS ACTIVATION – PRELIMINARY RESULTS
Giulio Anichini*, Zepeng Hu**, Maria Leiloglou**, Iani Gayo** Neekhil Patel*, Nelofer Syed*, Dipankar Nandi*, Kevin O’Neill*, Dan Elson**
*Department of Brain Sciences, Imperial College of London, **Hamlyn Centre of Robotics, Department of Surgery and Cancer, Imperial College of London
Arginine deprivation alters DNA damage response in arginosuccinate synthetase negative glioblastoma and potentiates standard of care
Avik Ghosh1,2, Richard Perryman1, Kevin O’Neill1, Nelofer Syed1
1 John Fulcher Molecular Neuro-oncology Laboratory, Department of Brain Sciences, Imperial College, London, UK 2 Department of Surgery and Cancer, Imperial College London, UK
Accurate Identification of Glial Malignancies from Peripheral Blood
Giulio Anichini1, Pooja Fulmali2, Kevin O’Neill1,3, Vineet Datta2, Timothy Crook1, Nelofer Syed1.
1 Department of Brain Sciences, Imperial College, London, UK; 2 Department of Research and Innovations, Datar Cancer Genetics, Nasik, India; 3 Imperial College Healthcare NHS Trust, London, UK
Optical Biopsies in Neurosurgery: Raman Spectroscopy
Download Presentation (PPTX)
Transcriptional silencing disprupts two levels of arginine biosynthesis in glioblastoma multiforme: a novel targeted therapeutic strategy for high grade gliomas
Presented June 2012 at the British Neurooncology Society Conference
Nelofer Syed1; Kevin O’Neill1; Mark Hughes1; Christiana LoNigro2; Laura Lattanzio2; Peter Szlosarek3; Federico Roncaroli1; Timothy Crook1.
1’John Fulcher’ Molecular Neuro-oncology Laboratory, BTRC, Imperial College, London, UK, 2Laboratorio Oncologia Translazionale, Cuneo, Italy, 3 Queen Mary University of London, Institute of Cancer and CR-UK Clinical Centre, Barts and The London School of Medicine, London
Determining the role of nicotinamide metabolism in chemosensitivity of glioblastoma multiforme
Mr Richard Perryman*, Mr Kevin O’Neill*, Dr Hector Keun+, Dr Nelofer Syed
Download Poster (PDF)
EXPRESSION OF TGFβ IN HUMAN GLIOMAS
HAMPTON T, CROISIER E, JANCZAR K, DAVIDSON-von HOLT SJ, TURKHEIMER FE, RONCAROLI F
Imperial College Healthcare NHS Trust and BTRC Research Group – London
Download Poster (PDF)
EVIDENCE OF MGMT-NEGATIVE MICROGLIA IN HIGH GRADE ASTROCYTOMAS
Strachan C. Mackenzie, Karolina Janczar, Emilie Croisier, Catherine Brock, S Davidson-von-Holt, Federico Turkheimer, Federico Roncarolia – Imperial College Healthcare NHS Trust – BTRC Research Group, London
Download Poster (PDF)
Endogenous Cortisol Biosynthesis in Human Gliomas
Presented April 2008 at the American Association of Cancer Research conference in San Diego
Karolina Janczar, Emilie Croisier, Bob Homapour, Kevin O’Neill, Amanda Forsyth, Federico Turkhemier, Manuel Deprez, Federico Roncaroli. BTRC / Imperial College of London, London, United Kingdom & Department of Neuropathology, University of Liege, Belgium
Download Poster (PDF)