BrainWear – Clinical Study of wrist worn trackers for monitoring activity in brain tumour patients

BTRC is funding a study of wrist worn trackers for monitoring activity in brain tumour patients, being run at Charing Cross Hospital (Imperial Healthcare NHS Trust)

Duration: 2018– 2023

Principal Investigator: Dr Matt Williams


There have been significant recent advancements in wearable technology wrist worn tracker devices which now allow us the opportunity to gather high-quality, physical activity data from patients in a non-obtrusive manner.

We believe that physical activity (PA) levels and their changes may indicate disease relapse in patients with primary and secondary brain tumours. Our aim is to assess the compliance and acceptability of patient-worn devices, such as wrist-worn trackers, to monitor this. We will also look at the levels of and changes in PA of patients, and the relationship between PA and conventional methods of monitoring disease relapse and progression, toxicity and quality of life.

Who can participate?
Patients aged between 18 and 90 years old with either high-grade glioma (HGG), low-grade glioma (LGG) or metastatic brain cancer, or matched normal healthy volunteers (main caregivers).

What does the study involve?
The participant is provided with an Axivity AX3 wrist-worn accelerometer device (similar to a wristwatch), which monitors their physical activity whilst they undergo their standard treatment and into the follow-up period. The patient is asked to wear the device for as long as they feel comfortable during the day and night, as it only needs to be taken off whilst swimming or taking a bath. We aim to collect a minimum of 6 months of data from each patient, though patients are free to withdraw from the study if they become too unwell, or should they choose to no longer take part. The device is CE marked, and meets the health and safety requirements required for clinical research.

What are the possible benefits and risks of participating?
The benefit of taking part in this study is to provide researchers with vital data for analysis, with the hope of being able to incorporate physical activity monitors into future Neuro-Oncology trials and standard follow-up, to better monitor brain tumour patient’s in the outpatient setting. Although there is no live feedback mechanism about physical activity to the patient at present, this is planned for after the study. There are no known risks to participants taking part in this study.

Read more here