Abstracts
Research funded by BTRC has produced numerous publications and presentations: here is a list of the published abstracts that our grants have facilitated.
Angiotensin signalling in GBM: AT2R as a novel therapeutic target
Authors: Mr. Alexander Renziehausen (Imperial College London), Dr. Jennifer Eschbacher (Barrow Neurological Institute), Dr. Andreas Tzakos (University of Ioannina), Dr. Kevin O’Neill (Imperial College London), Dr. Tim Crook (Southend University Hospital), Dr. Nelofer Syed (Imperial College London)
The ketogenic diet induces epigenetic changes that impact on the expression of microRNAs and chromatin modifying enzymes that play key roles in tumour development
Presented at BNOS June 2016
Jessica Preston 1; Julianna Stylianou 1, Quingyu Zeng 1, Sophie Glover 1, Kevin O’Neill 1; Adrienne C. Scheck 2; Eric C. Woolf 2, Nelofer Syed 1;
1: John Fulcher Molecular Neuro-Oncology Laboratory, BTRC, Imperial College, London, UK,
2: Neuro-Oncology Research, Barrow Neurological Institute, Phoenix, Arizona
The role of nicotinamide metabolism in chemosensitivity in glioblastoma multiforme
Presented at BNOS June 2016
Authors: Mr Richard Perryman, Mr Kevin O’Neil, Dr Hector Keun, Dr Nelofer Syed
Molecular profiling of Primary and Recurrent GBM reveal novel therapeutic opportunities
Presented at BNOS June 2016
Combiz Khozoie, Richard Perryman, Fernando Abaitua, Babar Vaqas, Kevin O’Neill, Nelofer Syed
Arginine deprivation using ADI-PEG20 leads to regression of an ASS-ve intracranial GBM tumour in mice and potentiates gamma irradiation of ASS+ve GBM in vitro.
Presented at AACR 2015
Abaitua F., Przystal JM., Hajitou A., O’Neill K and Syed N.
Dual systemic tumour targeting with ligand-directed phage and Grp78 promoter induces regression of glioblastoma
Dr. Amin Hajitou.
NB: This abstract won the “Best Scientific Abstract award at the 2012 British Neuro-oncology Society’s 2012 Annual Conference
Transcriptional silencing disrupts two levels of arginine biosynthesis in glioblastoma multiforme (GBM): a novel, targeted therapeutic strategy for GBM
Presented at BNOS June 2012
N Syed, F Roncaroli, K Janczar, P Singh, K O’Neil, C Lo Nigro, L Lattanzio, HM Coley, E Hatzimichael, J Bomalaski, P Szlosarek, T Crook.
Sonowand project: The safety and feasibility of intraoperative ultrasound to aid intrinsic tumour resection: a retrospective case-control series
Authors: Cameron Smail R, Brown A, Baldwin M, O’Neill KS
TSPO expression in human gliomas
Expression of the mitochondrial 18 kda translocator protein in Human astrocytomas and oligodendrogliomas and its association With endogenous cortisol synthesis
Karolina Janczar 1, Jonathan E Bowen 2, Nelofer Syed 1, Manuel Deprez 3, Emilie Croisier 1, Sally Davidson-Von Holt 4, Amanda Forsyth 5, Kevin O’Neill 1, James Van Dellen 1, Atsushi Sasaki 6, Federico E Turkheimer 1, Federico Roncaroli 1
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